{"id":19144,"date":"2026-03-18T18:24:44","date_gmt":"2026-03-18T17:24:44","guid":{"rendered":"https:\/\/www.cutislaxa.org\/?p=19144"},"modified":"2026-03-18T18:24:44","modified_gmt":"2026-03-18T17:24:44","slug":"les-problemes-cardiovasculaires-dans-la-cutis-laxa","status":"publish","type":"post","link":"https:\/\/www.cutislaxa.org\/fr\/les-problemes-cardiovasculaires-dans-la-cutis-laxa\/","title":{"rendered":"Les probl\u00e8mes cardiovasculaires dans la Cutis Laxa"},"content":{"rendered":"

Dr Ilse MEERSCHAUT<\/strong><\/p>\n

\"\"<\/p>\n

Selon une \u00e9tude portant sur 469 malades de CL, les troubles cardiovasculaires\u00a0sont pr\u00e9sents chez 50 \u00e0 80 % de ces malades. Il s\u2019agit principalement de tortuosit\u00e9, an\u00e9vrismes ou st\u00e9noses art\u00e9rielles. Plusieurs types de Cutis Laxa sont plus particuli\u00e8rement concern\u00e9s\u00a0: les mutations FBLN4, SLC2A10, LOX et EMILIN1 avec une tortuosit\u00e9 de l\u2019aorte et des branches aortiques principales et la mutation ELN avec de multiples d\u00e9sordres des valves cardiaques.<\/p>\n

\"\"<\/p>\n

Toutes ces formes demandent un suivi cardiovasculaire sp\u00e9cifique. Lors de la suspicion de l\u2019une ou l\u2019autres de ces mutations, selon la nouvelle classification, il est imp\u00e9ratif de mettre ce suivi en place sans attendre<\/p>\n

\"\"<\/p>\n

Il est n\u00e9cessaire de contr\u00f4ler la pression sanguine, mais aussi il faut \u00e9valuer et suivre de pr\u00e8s tout probl\u00e8me cardiaque et vasculaire (\u00e9chocardiographie, IRM du c\u0153ur, MR\/CT angiographie de la t\u00eate au pelvis).<\/p>\n

La fr\u00e9quence et l\u2019\u00e2ge auxquels doivent \u00eatre faits ces examens d\u00e9pendent du type de CL.<\/p>\n

Les diff\u00e9rences de suivi n\u00e9cessaires selon les mutations g\u00e9n\u00e9tiques n\u00e9cessitent que des guides de bonne pratique soient \u00e9tablis pour chaque mutation connue.<\/p>\n

\"\"<\/p>\n","protected":false},"excerpt":{"rendered":"

Dr Ilse MEERSCHAUT Selon une \u00e9tude portant sur 469 malades de CL, les troubles cardiovasculaires\u00a0sont pr\u00e9sents chez 50 \u00e0 80 % de ces malades. Il s\u2019agit principalement de tortuosit\u00e9, an\u00e9vrismes ou st\u00e9noses art\u00e9rielles. Plusieurs types de Cutis Laxa sont plus particuli\u00e8rement concern\u00e9s\u00a0: les mutations FBLN4, SLC2A10, LOX et EMILIN1 avec une tortuosit\u00e9 de l\u2019aorte et […]<\/p>\n","protected":false},"author":2,"featured_media":6776,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[61,60,66],"tags":[],"class_list":["post-19144","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-quoi-de-neuf","category-recherche","category-recherche-medecine-genetique"],"yoast_head":"\nLes probl\u00e8mes cardiovasculaires dans la Cutis Laxa - CUTIS LAXA INTERNATIONALE<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cutislaxa.org\/fr\/les-problemes-cardiovasculaires-dans-la-cutis-laxa\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Les probl\u00e8mes cardiovasculaires dans la Cutis Laxa - CUTIS LAXA INTERNATIONALE\" \/>\n<meta property=\"og:description\" content=\"Dr Ilse MEERSCHAUT Selon une \u00e9tude portant sur 469 malades de CL, les troubles cardiovasculaires\u00a0sont pr\u00e9sents chez 50 \u00e0 80 % de ces malades. Il s\u2019agit principalement de tortuosit\u00e9, an\u00e9vrismes ou st\u00e9noses art\u00e9rielles. Plusieurs types de Cutis Laxa sont plus particuli\u00e8rement concern\u00e9s\u00a0: les mutations FBLN4, SLC2A10, LOX et EMILIN1 avec une tortuosit\u00e9 de l\u2019aorte et […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.cutislaxa.org\/fr\/les-problemes-cardiovasculaires-dans-la-cutis-laxa\/\" \/>\n<meta property=\"og:site_name\" content=\"CUTIS LAXA INTERNATIONALE\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/CutisLaxaAssociation\/\" \/>\n<meta property=\"article:published_time\" content=\"2026-03-18T17:24:44+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.cutislaxa.org\/wp-content\/uploads\/2017\/07\/gene.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"300\" \/>\n\t<meta property=\"og:image:height\" content=\"300\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Marie-Claude\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Marie-Claude\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.cutislaxa.org\/fr\/les-problemes-cardiovasculaires-dans-la-cutis-laxa\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.cutislaxa.org\/fr\/les-problemes-cardiovasculaires-dans-la-cutis-laxa\/\"},\"author\":{\"name\":\"Marie-Claude\",\"@id\":\"https:\/\/www.cutislaxa.org\/#\/schema\/person\/2b5e58dca5a6f412607f985f2823d045\"},\"headline\":\"Les probl\u00e8mes cardiovasculaires dans la Cutis Laxa\",\"datePublished\":\"2026-03-18T17:24:44+00:00\",\"dateModified\":\"2026-03-18T17:24:44+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.cutislaxa.org\/fr\/les-problemes-cardiovasculaires-dans-la-cutis-laxa\/\"},\"wordCount\":207,\"publisher\":{\"@id\":\"https:\/\/www.cutislaxa.org\/#organization\"},\"articleSection\":[\"Quoi de neuf\",\"Recherche\",\"Recherche - 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